• AccuGeneBlock Service

Up to 1 Kb DNA fragment, with Fast Turnaround Time

AccuGeneBlock Service provides synthesis of double strand DNA fragments (less than 1 kb) in as little as 3 days. It is a brand new service offered by Bioneer, a leader in Gene Synthesis. AccuGeneBlock service provides you with your gene fragments at a great price with fast turnaround time so you can use it easily and quickly in synthetic biology research.

AccuGeneBlock products are supplied to you as 200 - 500 ng of lyophilized DNA fragments. The 5' ends are not phosphorylated, and there is a 3' A overhang for TOPO cloning as the default – Note that you may specify blunt-ends if you choose. Sequence verification is available on request.

AccuGeneBlocks are a low-cost alternative to Gene Synthesis and provide you with high quality DNA – Fast! They are the most convenient and affordable gene construction and/or modification tool available, and make synthetic biology methodology affordable and efficient for every lab.

Features and Benefits

Value Pricing
The best value for your research dollar ($95.00 for <500 bp)

Accurate and Fast Synthesis
Fully Automatic Synthesis makes it possible to synthesize high-quality genes in as little as 3 days

Easy Protein Synthesis
Gene fragments can be used for Protein Synthesis with PCR templates using ExiProgen™

Synthesis of large Genes
You may combine multiple AccuGeneBlocks in order to synthesize large Genes through Cloning,
Gene Assembly methods, etc.

Codon Optimization - Free of charge!
Complimentary codon optimization on request to enhance protein expression and functionality

Applications

Synthesis of large genes
It is possible to make the larger genes by combining multiple AccuGeneBlocks through cloning, Gene Assembly methods, etc. using the double strand DNA provided.

Protein Modification
Codon optimization can increase protein expression levels, and a mutant library derived from this process can provide proteins with enhanced function. Optimizations include the removal of secondary structure and/or repeat reduction, as well as optimization for expression in different organisms.

Antibody Construction
Antibodies which target specific diseases or proteins can be codon-optimized for maximum expression in the host organism. Also, an antibody library can be constructed to screen for the best antibody variant.

Organism Production Optimization
Optimization of gene expression to maximize the efficiency and yield of industrial biological production facilities

Gene Construction
Easy production of hard-to-clone DNA sequences.

Schematics of Gene Synthesis Process

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AccuGeneBlock Service
Price for Synthesis	<500 bp	$95.00 (sequencing excluded)
Price for Synthesis	501~1000 bp	$95.00 ( + $29.00/100 bp) (sequencing excluded)
Period of Synthesis	<500 bp	3~5 working days
Period of Synthesis	501~1000 bp	4~6 working days
Delivery Form	200 ~ 500 ng of lyophilized PCR product
Additional Service	Sequencing	<500 bp ($20.00) 501-1000 bp ($40.00)
	Increased Quantity	1 ug/$50.00
	Codon optimization	Free-of-Charge (via Email ordering only)

AccuGeneBlock Service may not be available if the gene sequence contains high or low GC content, repeatitive sequence,
homo-polymeric runs, etc. In these instances please use Bioneer's Gene Synthesis Service.
Available for gene of <1 kb in size.
Double-Stranded DNA with a single 3' A overhang is provided as a default. Blunt-ended DNA is available upon request.
Ordering through email is required for a gene with codon optimization.

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MSDS

Brochure

Quality Assurance

Bioneer is the holder of Quality Management System Certificates for the following standards

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